JOB TITLE:
Senior Scientist / Principal Investigator, Discovery Biology
LOCATION:
Boston, MA (On-site / Remote)
Company Overview:
CORE Biomedicine Inc. is a pioneering biotech startup dedicated to advancing novel therapies in oncology. We specialize in the development of small molecule drugs targeting novel pathways for the treatment of various cancers.
Position Overview:
We are seeking a dynamic and experienced individual, with strong multitasking skills, to support our ongoing drug discovery and development programs. The person will need to be on-site for the planning and execution of wet lab experiments across the various CORE preclinical oncology programs. This position will report to the Head of Biology.
Key Responsibilities:
- Design, execute, and interpret in vitro and in vivo experiments to test biological hypotheses and advance programs
- Build, optimize, and oversee robust biological assays relevant to disease biology and mechanism of action
- Provide scientific direction and leadership for ongoing projects
- Collaborate closely with medicinal chemistry, DMPK, toxicology, and translational teams to drive integrated decision-making
- Critically analyze data, identify risks, and propose clear experimental paths forward
- Present data and strategy at internal project reviews and leadership meetings
- Contribute to external scientific communications, including publications, posters, and presentations, as appropriate
- Help shape the scientific culture, experimental rigor, and discovery capabilities of a growing startup
- Maintain high standards of data quality, documentation, and scientific rigor
Qualifications:
- PhD in Biology, Biochemistry, Molecular Biology, Pharmacology, or a related life sciences field, M.Sc., or equivalent, with extensive relevant experience will also be considered
- 5+ years of postdoctoral and/or industry experience in drug discovery or translational research
- Strong track record of independent experimental design and scientific problem-solving
- Deep expertise in one or more relevant areas (e.g., cancer biology, gene regulation, cell signaling, functional genomics)
- Hands-on experience with cell-based assays, molecular biology techniques, and data analysis
- Demonstrated ability to mentor and lead scientists while remaining experimentally engaged
- Excellent communication skills and ability to clearly articulate complex biology, including presentations to leadership and at conferences
- Comfortable operating in a fast-paced, resource-conscious startup environment
Benefits:
- Competitive compensation
- Paid time off (vacation, holidays, and sick leave)
- Flexible work arrangements (hybrid or remote options where applicable)
- Professional development support (e.g., conference attendance, training)
- 401k, Bonus, Equity, Healthcare (Medical, Dental, Vision)
- Opportunity to work at the forefront of cancer research in a mission-driven startup environment
Application Process:
Please submit a resume/CV and a list of scientific publications outlining your qualifications and interest in the position. References may be requested during the interview process.